Gastrointestinal, Healthy Blood Glucose, and Healthy Cholesterol Support. 500 mg of berberine hydrochloride, an amount shown in clinical studies to support multiple body systems. Several clinical trials suggest that berberine can help support healthy blood glucose levels and healthy blood cholesterol levels already within the normal range. Can support gastrointestinal health.*Suggested Use: 1 capsule 1 to 2 times daily with meals.